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Different definition / meanings for the word "new drug application":
Following phase III of clinical testing, the drug sponsor applies for a new drug application, which is reviewed by the FDA. If the FDA finds the results favorable, the drug company can market the drug for conditions/ diseases, which are applicable to phase testing results.
Different definition / meanings for the word "drug resistance":
Occurs when the virus a person is infected with is no longer sensitive to the medications taken. Even when the viral load is undetectable, a small amount of virus is still replicating. The ‘copies’ (of the replicating viruses) that survive are those that the drug cannot suppress. The surviving copies have genes that have mutated to elude capture by the drug. Sooner or later, this mutated virus reaches a critical mass and ‘breaks through’
